How Prostate Cancer Works

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How Prostate Cancer Works

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We care about our dads, uncles, grandpas – and all of the men in our lives. So why not understand the basics underlying the 2nd largest cancer killer in America and the UK among men (and 6th worldwide)? We’ll strip down the process of cell regulation, cancer, and what is known about prostate cancer.

Written and created by Mitchell Moffit (twitter @mitchellmoffit) and Gregory Brown (twitter @whalewatchmeplz).


Music by Mitchell Moffit

Art by Gregory and Mitchell

–A Few Papers/Sources–

1) Dall’Era, M., Cooperberg, M., Chan, J., Davies, B., Albertsen, P., Laurence, K., Warlick, C., Holmberg, L., Bailey, D.,Wallace, M., Kantoff, P., Carroll, P. (2008) Active surveillance for early-stage prostate cancer. Cancer. 112: 1650-1659

2) Whittemore, A., Kolonel, L., Wu, A., John, E., Gallagher, R., Howe, G., Burch, J., Hankin, J., Dreon, D., West, D. (1995) Prostate cancer in relation to diet, physical activity, and body size in blacks, whites and Asians in the Unites States and Canada. Journal of the National Cancer Institute. 87: 652

3) Gallagher, R., Fleshner, N. (1998) Prostate cancer: 3. Individual risk factors. Canadian Medical Association. 159(7): 807-813

4) Aldercreutz, H., Markannen, H., Watanabe, S. (1993) Plasma concentrations of phytoestrogens in Japanese men. Lancet. 342: 1209-1210

5) Peterson, G., Barnes, S. (1993) Genistein and biochanin A inhibit the growth of human prostate cancer cells but not epidermal growth facto receptor tyrosine autophosphorylation. Prostate. 22: 335-345

6) El-Barjourmi, K. (1991) The role of selenium in cancer prevention. In: DeVita VT, Hellman, S., Rosenberg, S., editors. Cancer prevention. Philadelphia: JB Lippincott. 1-15

7) Clark, L., Combs, G., Turnbull, B., Slate, E., Chalker, D., Chow, J. (1996) Effects of selenium supplementation for cancer prevention in patients with carcinoma of the skim. Journal of the American Medical Association. 267: 1957-1963

8) Redman, M., Tangen, C., Goodman, P., Lucia, M., Coltman, C., Thompson, I. (2008) Finsteride does not increase the risk of high-grade prostate cancer: a bias-adjusted modeling approach. Cancer Prevention and Research. 1(3): 174-181

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